Calinescu, AA, Núñez,
FJ, Koschmann, C, Kolb, BL, Lowenstein, PR, Castro, MG. (2015) Transposon Mediated Integration of
Plasmid DNA into the Subventricular Zone of Neonatal Mice to Generate Novel
Models of Glioblastoma. Journal of
Visualized Experiments, February 22, 2015.
PMCID: PMC4354658. - Mineharu Y, Kamran N, Lowenstein PR, and Castro
MG. (2014) Blockade of mTOR
signaling via Rapamycin Combined with Immunotherapy Augments Anti-glioma
Cytoxic and Memory T cells’ functions. Molecular
Cancer Therapeutics, December 13, 2014; (12):3024-36. PMCID: PMC4258521.
- Candolfi M, Yagiz K, Wibowo M, Ahlzadeh G, Puntel M, Kamran
N, Paran C, Ghiasi H, Lowenstein PR, Castro MG. (2014) Temozolomide does
not impair gene therapy-mediated antitumor immunity in syngenic brain tumor
models. Clinical Cancer Research. March 15, 2014;20(6):1555-65. Epub February 5, 2014. Portrayed on the cover of the March, 2014
issue. PMCID: PMC3959570.
Castro MG, Lowenstein PR. (2013) Neuro-oncology: The long and winding road --gene therapy for
glioma. Nature Reviews Neurology 2013 November; 9(11): 609-10.
Epub 2013 September 24. PMCID:
PMC3928109.
- Candolfi M, King GD, Yagiz K, Curtin JF, Mineharu Y, Muhammad
AG, Foulad D. Kroeger KM, Josien R, Lowenstein PR, and Castro, MG. (2012) Plasmacytoid Dendritic Cells in the
Tumor Microenvironment: Immune Targets
for Glioma Therapeutics. Neoplasia, 2012
Aug; 14(8):757-70. PMCID: PMC3431182.
- Yang J, Sanderson N,
Wawrowsky K, Castro MG, Lowenstein PR. (2010) Kupfer-type immunological
synapses are not relevant to cytolytic T-cell function in vivo. Proceedings of the National Academy of Sciences,
USA 107(10):4716-4721. PMCID: PMC2842057.
- Larocque D, Sanderson NRS, Bergeron J, Curtin J, Girton J, Wibowo M,
Bondale N, Kroeger KM, Yang J, Lacayo LM, Reyes KC, Farrokhi C, Pechnick RN,
Castro MG, Lowenstein PR, (2010) Exogenous fms-like tyrosine kinase 3 ligand
overrides brain immune privilege and facilitates recognition of a neo-antigen
without causing autoimmune neuropathology. Proceedings of the National Academy of Sciences, USA. 107(32):14443-14448. PMCID: PMC2922551.
- Candolfi M, Xiong W, Yagiz K, Liu C, Muhammad AK, Puntel M,
Foulad D, Lowenstein PR, Castro MG. (2010) Gene therapy-mediated
delivery of targeted cytotoxins for glioma therapeutics. Proceedings of the National Academy of Sciences, USA, 107(46):20021-20026.
Epub 2010 Oct 28. PMCID: PMC2993419.
- Muhammad AKM, Puntel M, Candolfi M, Salem A, Yagiz K,
Farrokhi C, Kroeger KM, Xiong W, Curtin JF, Liu C, Lawrence K, Bondale NS,
Lerner J, Baker GJ, Foulad D, Pechnick RN, Palmer D, Ng P, Lowenstein PR, Castro
MG. (2010) Study of the Efficacy, biodistribution and safety profile of
therapeutic gutless adenovirus vectors as a prelude to a Phase 1 Clinical Trial
for Glioblastoma. Clinical Pharmacology
& Therapeutics, 88(2):204-213. PMCID:
PMC2908190.
- Curtin JF, Liu N, Candolfi M, Ziong W, Assi H, Yagiz Y, Michelsen K,
Kroeger K, Liu C, Muhammad A, Arditi M, Comin-Anduix B, Ribas A, Lowenstein PR,
Castro MG. (2009) HMGB1 mediates endogenous TLR2 activation and brain tumor
regression. PLoS Medicine Jan 13;
6(1):e10; PMCID: PMC2621261.
- Candolfi M, Yagiz
K, Foulad D, Alzadeh GE, Tesarfreund M, Muhammad AKM, Puntel M, Kroeger KM, Liu
C, Lee S, Curtin J, King GD, Lerner J, Sato K, Lowenstein PR, Castro MG.
(2009) Release of HMGB1 in response to proapoptotic glioma killing strategies:
efficacy and neurotoxicity. Clinical
Cancer Research 15(13):4401-4414.
Portrayed on the Highlights Section. PMCID: PMC2769255.
- Ali S, King G, Curtin J, Candolfi M, Xiong W, Liu C, Puntel
M, Cheng Q, Prieto J, Ribas A, Kupiec-Weglinski J, van Rooijen N, Lassman H,
Lowenstein PR, Castro MG. (2005) Combined immuno-stimulation and
conditional cytotoxic gene therapy provide long term survival in a large glioma
model. Cancer Research. August 15, 2005; 65(16):7194-7204. Portrayed on the highlights section of Cancer Research. PMCID:
PMC1242178.
- Umana P, Gerdes CA, Stone D, Davis JR, Ward D, Castro MG,
Lowenstein PR (2001) Efficient FLPe recombinase enables scalable production of
helper-dependent adenoviral vectors with negligible helper-virus contamination.
Nature Biotechnology,
19:582-585. PMID: 11385466.
- Thomas CE, Schiedner G, Kochanek S, Castro MG,
Lowenstein PR (2000) Peripheral infection with adenovirus causes unexpected
long-term brain inflammation in animals injected intracranially with first
generation, but not with high-capacity adenovirus vectors: towards realistic
long-term neurological gene therapy for chronic diseases. Proceedings of the National Academy of Sciences, USA,
97:7482-7487. PMCID: PMC16571.
- Dewey RA, Morrissey G, Cowsill C, Stone D, Dodd NJF,
Bolognani F, Southgate TD, Klatzmann D, Castro MG, Lowenstein PR. (1999)
Chronic brain inflammation and persistent HSV1-TK expression in survivors of
syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for
clinical trials. Nature Medicine,
November, 1999;5(11), 1256-1263 Portrayed on the cover of the journal. PMID 10545991.
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