Baker GJ, Castro MG, and Lowenstein PR. (2015) Isolation and
Flow Cytometric Analysis of Glioma-Infiltrating Peripheral Blood Mononuclear
Cells. Journal of Visualized Experiments, Epub 28 Nov 2015. - Baker G, Chockley P,
Yadav V, Doherty R, Ritt M, Sivaramakrishnan S, Castro MG, Lowenstein PR. (2014) Natural killer cells eradicate
galectin-1 deficient glioma in the absence of adaptive immunity. Cancer
Research, 74:5079-90. PMCID: PMC4184887.
- Baker GJ, Yadav VN, Motsch S,
Koschmann C, Calinescu A, Mineharu Y, Carmelo-Piragua S, Orringer D, Bannykh S,
Nicholas WS, deCarvalho AC, Mikkelsen T, Castro MG, Lowenstein PR.
(2014) Mechanisms of Glioma Formation: Iterative Perivascular Glioma Growth and
Invasion Leads to Tumor Progression, VEGF-independent Vascularization and
Resistance to Anti-angiogenic Therapy. Neoplasia. 16:543-561. Portrayed
on the cover of the July, 2014 issue. PMID: 25117977.
- Lynes J, Wibowo M, Koschmann C, Baker G, Saxena V, Ghulam Muhammad AK,
Bondale N, Klein J, Assi H, Lieberman P, Castro MG, Lowenstein PR. (2014) Lentiviral-Induced High-Grade Gliomas
in Rats: The Effects of PDGFB, HRAS-G12V, AKT, and IDH1-R132H. Neurotherapeutics, 11:623-35. PMCID: PMC4121445.
Castro MG, Lowenstein PR. (2013) Neuro-oncology: The long and winding road --gene therapy for
glioma. Nature Reviews Neurology 2013 November; 9(11): 609-10.
Epub 2013 September 24. PMCID:
PMC3928109.
- Sanderson NS, Puntel M, Kroeger
KM, Bondale NS, Swerdlow M, Iranmanesh N, Yagita H, Ibrahim A, Castro MG, Lowenstein
PR, (2012)
Cytotoxic immunological synapses do not restrict the action of interferon-γ to
antigenic target cells. The Proceedings of the National Academy of
Sciences, USA. 109(20): 7835-40.
PMCID: PMC3356634.
- Zirger JM, Puntel M, Bergeron J, Wibowo M, Moridzadeh R, Bondale N,
Barcia C, Kroeger KM, Liu C, Castro MG, Lowenstein PR. (2012) Immune-mediated
Loss of Transgene Expression From Virally Transduced Brain Cells Is
Irreversible, Mediated by IFNγ, Perforin, and TNFα, and due to the Elimination
of Transduced Cells. Molecular Therapy, 20:808-19. PMCID:
PMC3321600.
- Larocque D, Sanderson NRS,
Bergeron J, Curtin J, Girton J, Wibowo M, Bondale N, Kroeger KM, Yang J, Lacayo
LM, Reyes KC, Farrokh C, Pechnick RN, Castro MG, Lowenstein PR, (2010)
Exogenous fms-like tyrosine kinase 3 ligand overrides brain immune privilege and facilitates recognition of a
neo-antigen without causing autoimmune neuropathology. The Proceedings of the National Academy of Sciences, USA,
107:14443-14448. PMCID: PMC2922551.
- Yang J, Sanderson N, Wawrowsky K, Castro MG, Lowenstein PR.
(2010) Kupfer-type immunological synapses are not relevant to cytolytic T-cell
function in vivo. Proceedings of the National Academy of Sciences, USA 107:4716-21 Portrayed on the cover. PMCID: PMC2842057.
- Mineharu Y, King G, Muhammad AKM, Bannykh S, Kroeger K, Liu C, Lowenstein
PR, Castro MG. (2011) Engineering the brain tumor microenvironment
enhances the efficacy of dendritic cells' vaccination: implications for
clinical trials design. Clinical Cancer Research 17: 4705-4718.
- Curtin JF, Liu N, Candolfi M,
Ziong W, Assi H, Yagiz Y, Edwards MR, Michelsen KS, Kroeger KM, Liu C, Muhammad
AK, Clark MC, Arditi M, Comin-Anduix B, Ribas A, Lowenstein PR, Castro
MG. (2009) HMGB1 mediates endogenous TLR2 activation and brain tumor
regression. PLoS Medicine,
6:e10. PMCID: PMC2621261.
- Ghulam Muhammad AK, Candolfi
M, King GD, Foulad D, Yagiz K, Mineharu Y, Kroeger K, Treuer KA, Nichols WS,
Sanderson NS, Lowenstein PR, Castro MG. (2009) Antiglioma immunological
memory in response to conditional cytotoxic/immune-stimulatory gene therapy:
humoral and cellular immunity lead to tumor regression Clinical Cancer
Research 15:6113-6127. PMCID:
PMC2796687.
- Barcia C, Wawrowsky K, Barrett RJ, Liu C,
Castro MG, Lowenstein PR, (2008) In
vivo polarization of IFN-g at Kupfer and non-Kupfer immunological synapses during the clearance of
virally infected brain cells. The Journal of Immunology,
180:1344-1352.
Portrayed on the cover; PMCID: PMC2629497.
- Barcia C, Thomas C, Curtin J, King G, Wawrowsky K, Candolfi M, Kroeger
K, Boyer O, Kupiec-Weglinski J, Klatzmann D, Castro MG, Lowenstein PR,
(2006) In Vivo mature effector
immunological synapses forming supramolecular activation cluster (SMAC) mediate
clearance of virally infected astrocytes from the brain. The Journal of Experimental Medicine
203(9):2095-2107
Portrayed on the cover, reviewed in
detail by Science, Cell, and Faculty of 1000-Biology. PMCID:
PMC1997281.
- Ali S, King GD, Curtin JF,
Candolfi M, Xiong W, Liu C, Puntel M, Cheng Q, Prieto J, Ribas A,
Kupiec-Weglinski J, van Rooijen N, Lassman H, Lowenstein PR, Castro MG.
(2005) Combined immuno- stimulation and conditional cytotoxic gene therapy
provide long term survival in a large glioma model. Cancer
Research, 65:7194-7204. Portrayed on the highlights section of Cancer
Research. PMCID: PMC1242178.
- Umana P, Gerdes CA, Stone D, Davis JR, Ward D, Castro MG, Lowenstein
PR. (2001) Efficient FLPe recombinase enables scalable production of
helper-dependent adenoviral vectors with negligible helper-virus contamination.
Nature Biotechnology, 19:582-585.
PMID: 11385466.
- Thomas CE, Scheidner G, Kochanek
S, Castro MG, Lowenstein PR. (2000) Peripheral infection with adenovirus
causes unexpected long-term brain inflammation in animals injected
intracranially with first generation, but not with high-capacity adenovirus
vectors: toward realistic long- term neurological gene therapy for chronic
diseases. Proceedings of the National Academy of Sciences, USA
97:7482-7487. PMCID: PMC16571.
- Dewey R, Morrissey G, Cowsill C, Stone D, Dodd N, Southgate T, Klatzmann
D, Lassmann H, Castro MG, Lowenstein PR. (1999) Chronic brain
inflammation and persistent HSV-1 thymidine kinase expression in survivors of
syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for
clinical trials. Nature Medicine,
5:1256-1263. Portrayed on cover.
PMID: 10545991.
|